The two-car crash was reported on Route 15 near Basford Road in Point of Rocks shortly after 1:50 p.m., Frederick County Fire & Rescue said.
Two occupants were trapped following the collision, requiring a request for additional rescue squads.
Two troopers were then called to land police helicopters near Route 15.
Both victims had been extricated as of about 2:20 p.m., authorities said in an update.
Route 15 was shut down in both directions at Basford Road as crews responded. Drivers were asked to use an alternate route.
This is a developing story. Check Daily Voice for updates.
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